L-Ergothioneine Powder (CAS 497-30-3) | 99% Pure EGT Powder Manufacturer & Bulk Supplier – Shaanxi Bolin Biological

L-Ergothioneine Powder is a high-purity antioxidant cosmetic and nutraceutical ingredient manufactured by Shaanxi Bolin Biological (BOVLIN). With 99% purity, excellent stability, and broad formulation compatibility, this premium EGT powder is widely used in cosmetics, dietary supplements, pharmaceutical research, ophthalmic products, and advanced health applications requiring oxidative stress protection.

What Is L-Ergothioneine Powder?

 L-Ergothioneine (EGT) is a naturally occurring thiol/thione amino acid derivative originally discovered in ergot fungi and later identified in mushrooms, certain bacteria, and various food sources. Unlike conventional antioxidants, L-Ergothioneine is transported into cells through a dedicated transporter protein known as OCTN1 (Organic Cation Transporter Novel Type 1), enabling targeted accumulation in tissues exposed to oxidative stress.

 Because the human body cannot synthesize meaningful amounts of ergothioneine, dietary intake or supplementation serves as the primary source. Research has shown that ergothioneine accumulates in tissues with elevated oxidative activity, leading scientists to investigate its role in cellular protection, healthy aging, and advanced antioxidant formulations.

 Today, high-purity 99% L-Ergothioneine Powder has become an important functional ingredient for cosmetic, nutraceutical, pharmaceutical, ophthalmic, and biotechnology industries.

Product Specifications

Identity Information

 Product Name: L-Ergothioneine Powder

 Common Name: EGT Powder

 CAS Number: 497-30-3

 Application: Cosmetic Raw Material / Nutraceutical Ingredient

 Shelf Life: 2 Years

 Appearance: White Powder

 MOQ: 1kg

 Sample: Available

Physical Specifications

Appearance

 White powder meeting industrial cosmetic and nutraceutical manufacturing standards.

Purity

 99% L-Ergothioneine

Particle Size

 95% passes through 80 mesh.

Odor

 Characteristic.

Taste

 Characteristic.

Loss on Drying

 ≤ 5.0%

Ash

 ≤ 5.0%

Allergens

 None detected.

Heavy Metal Specifications

Total Heavy Metals

 NMT 10 ppm

Arsenic

 NMT 2 ppm

Lead

 NMT 2 ppm

Cadmium

 NMT 2 ppm

Mercury

 NMT 2 ppm

Microbiological Specifications

Total Plate Count

 Maximum 10,000 cfu/g

Yeast & Mold

 Maximum 1,000 cfu/g

E. coli

 Negative

Salmonella

 Negative

 These specifications support the quality requirements of cosmetic, nutraceutical, and research-grade manufacturing environments.

How L-Ergothioneine Works: Four Key Antioxidant Mechanisms

1. Free Radical Scavenging Activity

 L-Ergothioneine functions as a powerful antioxidant capable of neutralizing reactive oxygen species (ROS) generated through environmental exposure, UV radiation, pollution, and normal cellular metabolism.

 By reducing oxidative stress, it helps support cellular integrity and ingredient stability within cosmetic and nutraceutical formulations.

2. Metal Ion Chelation

 Transition metals such as iron and copper can catalyze oxidative reactions that accelerate cellular damage.

 L-Ergothioneine demonstrates metal-chelating activity that may help reduce oxidation induced by these catalytic metals, contributing to enhanced product performance and biological protection.

3. Mitochondrial Protection

 Mitochondria are among the primary sites of oxidative stress generation.

 Research indicates that ergothioneine accumulates in tissues susceptible to oxidative damage and may contribute to mitochondrial defense mechanisms through its selective cellular transport system.

4. Cellular Defense Support

 The unique OCTN1 transporter actively concentrates ergothioneine in cells and tissues exposed to oxidative challenges. This selective uptake differentiates EGT from many conventional antioxidants and contributes to its growing interest in advanced health and beauty applications.

Applications of L-Ergothioneine Powder

Cosmetic Formulations

Anti-Aging Skincare

 Cosmetic grade L-Ergothioneine is increasingly incorporated into premium anti-aging formulations designed to help protect skin from oxidative stress caused by environmental aggressors.

Brightening Products

 Formulators frequently combine EGT powder with niacinamide, vitamin C derivatives, ferulic acid, and other antioxidants in advanced skincare systems.

Sun Care Products

 L-Ergothioneine is used in antioxidant support systems intended to complement protective skincare formulations.

Eye Care Formulas

 Its excellent stability profile makes it suitable for eye creams, serums, and sensitive skin applications.

Dietary Supplements

 L-Ergothioneine is increasingly used in healthy aging, cellular wellness, antioxidant support, and longevity-oriented supplement products.

 The ingredient is frequently combined with NMN, resveratrol, CoQ10, spermidine, glutathione, and other advanced nutraceutical compounds.

Pharmaceutical Research

 Researchers continue to investigate ergothioneine's biological properties related to oxidative stress modulation, cellular protection, and tissue preservation.

 Its unique transporter-mediated distribution profile makes it an attractive candidate for advanced pharmaceutical development programs.

Organ Preservation Research

 L-Ergothioneine has been studied as a component of organ preservation solutions because oxidative stress plays an important role during transplantation procedures.

 Industrial and academic research organizations continue evaluating its potential utility in preservation technologies.

Ophthalmic Applications

 Oxidative stress is recognized as a significant factor in ocular tissue aging.

 As a result, L-Ergothioneine has attracted attention in ophthalmology research and eye-health product development.

Functional Foods and Beverages

 Food manufacturers utilize ergothioneine in premium functional nutrition products targeting antioxidant support and wellness-conscious consumers.

Animal Nutrition and Feed

 Animal health manufacturers are exploring EGT powder as a functional ingredient in specialty feed and companion animal nutrition products.

Safety Profile and EFSA Assessment

EFSA Safety Evaluation

 The European Food Safety Authority (EFSA) conducted a comprehensive evaluation of synthetic L-Ergothioneine and concluded that it is safe under the proposed conditions of use for adults, infants, toddlers, pregnant women, and breastfeeding women.

Daily Intake Assessment

 EFSA reported maximum anticipated daily exposures of:

· Infants: 2.82 mg/kg body weight/day

· Toddlers: 3.39 mg/kg body weight/day

· Adults, including pregnant and breastfeeding women: 1.31 mg/kg body weight/day

 The assessment identified a No Observed Adverse Effect Level (NOAEL) of 800 mg/kg body weight/day and concluded that the resulting safety margins were sufficient for the evaluated populations.

Regulatory Considerations

 Product developers should independently verify regulatory status, permitted use levels, labeling requirements, and regional compliance obligations before commercialization in target markets.

Quality Assurance and Manufacturing Standards

International Certifications

 Shaanxi Bolin Biological maintains manufacturing and quality management systems supported by:

· HACCP Certification

· ISO Certification

· HALAL Certification

· ORGANIC Certification

· KOSHER Certification

Quality Control Program

 Each production batch undergoes testing for identity, purity, microbiological safety, heavy metals, particle size distribution, moisture content, and appearance.

 Certificates of Analysis (COA) are available upon request to support customer qualification and regulatory documentation requirements.

Packaging Options

Standard Packaging

Small Quantity Packaging

 1kg aluminum foil bag

Industrial Packaging

 25kg cardboard drum

 Packaging is designed to maintain product stability during international transportation and long-term storage.

Storage and Shelf Life

 Store in a cool, dry place away from direct sunlight and excessive humidity.

 Under recommended storage conditions, the product maintains a 2-year shelf life.

Global Logistics and Supply Chain Support

Shipping Methods

 BOVLIN supports worldwide delivery through multiple logistics channels:

· DHL

· UPS

· FedEx

· TNT

· EMS

· Air Cargo

 Shipping solutions can be customized according to destination country, customs requirements, and delivery timelines.

Payment Methods

 Accepted payment options include:

· T/T (Bank Transfer)

· Western Union

· PayPal

· Credit Card

· Cash

Why Choose Shaanxi Bolin Biological (BOVLIN)?

Specialized Ingredient Manufacturing

 Shaanxi Bolin Biological focuses on botanical extracts, cosmetic ingredients, nutraceutical raw materials, and functional health ingredients supplied to international manufacturers.

Stable Supply Capacity

 Through established production and inventory management systems, BOVLIN supports both pilot-scale development projects and large-volume commercial procurement.

Global Export Experience

 The company serves customers across North America, Europe, Southeast Asia, the Middle East, and other international markets.

Technical Documentation Support

 Customers can request COAs, specification sheets, quality documentation, and export-related materials necessary for supplier qualification processes.

Scientific and Market Significance of Ergothioneine

 Recent scientific literature has highlighted ergothioneine as a unique diet-derived antioxidant characterized by selective uptake through the OCTN1 transporter and long-term tissue retention. Researchers continue exploring its role in cellular protection and healthy aging pathways.

 At the same time, global cosmetic manufacturers are increasingly seeking advanced antioxidant ingredients capable of supporting modern anti-pollution, anti-aging, and skin-defense formulations. This trend has contributed to growing commercial interest in cosmetic-grade L-Ergothioneine across premium skincare categories.

 The combination of scientific attention, regulatory acceptance, and formulation versatility positions EGT powder as one of the most promising next-generation antioxidant raw materials for both health and beauty industries.

Frequently Asked Questions (FAQ)

1. What is the purity of BOVLIN L-Ergothioneine Powder?

 The standard specification is 99% pure L-Ergothioneine.

2. What is the CAS number of L-Ergothioneine?

 The CAS number is 497-30-3.

3. Is cosmetic grade L-Ergothioneine suitable for anti-aging skincare products?

 Yes. Cosmetic formulators commonly use EGT powder in antioxidant serums, creams, lotions, and premium skincare products.

4. What is the minimum order quantity?

 The standard MOQ is 1kg.

5. Can I obtain a sample before placing a bulk order?

 Yes. Samples are available for formulation testing and quality evaluation.

6. Which certifications are available?

 The product is supported by HACCP, ISO, HALAL, ORGANIC, and KOSHER certifications.

7. What packaging options are offered?

 Standard packaging includes 1kg aluminum foil bags and 25kg cardboard drums.

8. Which shipping methods are available?

 Orders can be shipped through DHL, EMS, UPS, FedEx, TNT, or air freight depending on destination and logistics requirements.

9. Is L-Ergothioneine compatible with other antioxidants?

 Yes. It is commonly formulated with vitamin C derivatives, glutathione, coenzyme Q10, niacinamide, resveratrol, and related antioxidant ingredients, subject to formulation validation.

10. How can buyers verify product quality?

 BOVLIN can provide Certificates of Analysis, specification sheets, and supporting quality documentation for supplier qualification and regulatory review.

Conclusion

 As demand grows for scientifically supported antioxidant ingredients, L-Ergothioneine Powder (CAS 497-30-3) has emerged as a high-value raw material for cosmetic, nutraceutical, pharmaceutical, ophthalmic, and functional food applications. With 99% purity, comprehensive quality controls, internationally recognized certifications, and flexible global supply capabilities, Shaanxi Bolin Biological (BOVLIN) offers a dependable source of bulk L-Ergothioneine powder for manufacturers seeking premium-grade antioxidant solutions.

Brand: Shaanxi Bolin Biological (BOVLIN) Contact Number: +86-29-84355551 Email: sales1@bovlin.com